Center for Undergraduate Research in Viterbi Engineering (CURVE) Fellowship
Biomedical Engineering Research Positions
** Please note that all lab positions for CURVE have been filled for the 2022-23 academic year. **
Applied Movement and Pain Laboratory (AMPL)
Faculty / PI: Jason Kutch
Research Website: https://sites.usc.edu/ampl/
Lab Description: The Applied Movement & Pain Laboratory (AMPL) is directed by Jason J. Kutch. Work in AMPL is at the intersection of chronic pain and movement control. We are particularly interested in how the nervous system controls pelvic floor muscles, as well as how brain dysfunction contributes to chronic pelvic pain. Current research in AMPL is focused on developing non-invasive brain stimulation approaches for augmenting chronic pain treatment.
Information Session Recording
Faculty / PI: Eunji Chung
Research Website: biomaterials.usc.edu https://chunglaboratory.com/
Lab Description: The Chung research group focuses on drug delivery, nanomedicine, and regenerative engineering to generate biomaterial strategies to address the limitations of clinical solutions. In particular, we are interested in biomimetic nanoparticles that can be designed to deliver molecular signals to report back on or influence the behavior of diseased tissue for biomedical applications. In addition, we are harnessing our expertise in combining bioactive scaffolds with novel stem cell sources for complex regeneration of hierarchically-ordered tissues and organs. Our group is highly interdisciplinary as our research is positioned at the intersection of engineering, biology, and medicine, and we work with a variety of collaborators to translate our materials towards clinical use.
Faculty / PI: Dominique Duncan
Research Website: https://sites.usc.edu/duncanlab/
Lab Description: Welcome to the Duncan Lab, an interdisciplinary research group in the Laboratory of Neuro Imaging at the USC Stevens Neuroimaging and Informatics Institute. We are a group of neuroscientists, engineers, mathematicians, computer programmers, chemists, and data scientists who share a common goal of addressing challenges to neuroscience and public health via big data. We do so by working at the intersection of neuroimaging, signal processing, informatics, and machine learning. We leverage computational tools in conjunction with mechanistically oriented neuroimaging to develop analytic tools for multimodal data, build centralized archives for data and algorithms, and promote large-scale collaborative research. Currently, we focus on applications in traumatic brain injury, epilepsy, novel devices for intracranial stimulation, and COVID-19.
Gait Rehabilitation and Motor Learning Lab
Faculty / PI: Kristan Leech
Research Website: https://sites.usc.edu/grmllab/
Lab Description: The GRML Lab at USC is an interdisciplinary lab housed in the Division of Biokinesiology and Physical Therapy. We are researchers and clinician-scientists with diverse academic backgrounds that span systems neuroscience, biomechanics, engineering, and physical therapy. Our primary research goals are to – (1) develop innovative, effective approaches to gait rehabilitation in individuals with neurologic injury and translate these results into practical clinical interventions; (2) understand the impact of cognitive dysfunction on an individual’s ability to learn a new movement.
Faculty / PI: Andrei Irimia
Research Website: https://gero.usc.edu/labs/irimialab/
Lab Description: In our laboratory, we leverage neuroimaging and electrophysiology to study neurovascular injury, trauma-induced neural plasticity and atypical neurodegeneration. We integrate brain mapping techniques with machine intelligence and computational biology approaches to investigate how brain connectivity alterations caused by vascular brain injury add to the neurocognitive deficits of aging victims of concussions, cerebral amyloid angiopathy or dementia. We are interested in how vascular disease affects brain aging trajectories, and in the relationship between brain trauma and neurodegenerative diseases.
Information Session Recording
JVL Orthopaedic Biomechanics Research Center
Faculty / PI: Edward Abrams
Research Website: http://jvlresearch.org
Lab Description: The J. Vernon Luck, Sr., M.D. Orthopaedic Research Center, known as JVL, is located on the Downtown Campus of Orthopaedic Institute for Children, founded as Orthopaedic Hospital in 1911. The Research Center was dedicated to J. Vernon Luck, Sr., M.D., in 1986. The JVL Research Center is internationally recognized for advances in implant performance, including wear, fixation, retrieval analysis, and clinical outcome, as well as fracture, healing and repair.
Laboratory for Design of Medical and Analytical Devices (MAD Lab)
Faculty / PI: Maral Mousavi
Research Website: https://sites.usc.edu/mousavi/
Lab Description: Our research focuses on developing engineered tools for improving healthcare and patient outcomes. We are motivated to develop affordable point-of-care diagnostics to make healthcare accessible to all, and to develop new bioanalytical tools to help unravel the pathophysiology of diseases. The group has four project areas: (i) development of affordable point-of-care diagnostics to make healthcare accessible to all, (ii) development of wearable devices and textile-based sensors for detection of markers in sweat, (iii) use of fluorous compounds as novel materials for designing sensors with improved selectivity and response time, (iv) designing neural probes for in vivo measurement of acetylcholine dynamics in the brain (important in Alzheimer’s disease and other neurodegenerative diseases)
Laboratory for for Living Systems Engineering
Faculty / PI: Megan McCain
Research Website: https://livingsystemsengineering.usc.edu/
Lab Description: To develop safe and effective cures for human diseases, we need reliable models of human tissues to establish the underlying biology and screen drugs. However, existing model systems, such as rodents and conventional cell culture approaches, fall short in recapitulating critical features of native human tissues and providing easily-accessible functional outputs. To address this need, we engineer micro-scale mimics of native healthy and diseased human tissues that provide meaningful physiological outputs and are scalable for downstream applications, such as drug screening. We focus primarily on cardiac and skeletal muscle.
To fabricate these platforms, we are advancing and integrating three core technologies: 1. Establishing renewable sources of differentiated human cells. 2. Engineering biomimetic cellular microenvironments. 3. Developing tools to quantify tissue structure and function.
We combine these technologies towards three primary applications: 1. Establishing fundamental insight into human tissue structure-function relationships. 2. Elucidating cellular mechanisms of human diseases.
Published on June 8th, 2021
Last updated on October 10th, 2022